Thianthrene

Overview

Thianthrene is a potent and orally active inhibitor of Leishmania donovani pteridine reductase 1 ( PTR1 ). Thianthrene is a sulfur-containing tricyclic molecule distributed widely within the macro-structure of hydrocarbon fossil fuels. Thianthrene inhibits the intracellular amastigotes of Leishmania donovani ( IC 50 = 23 μM). Thianthrene has a moderate anthelmintic activity. Thianthrene appears to inhibit RNA function and subsequent protein production. Thianthrene can stimulate liver regeneration in vivo.

Application

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Product Information

• Catalog No.: HY-W014120
• CAS No.: 92-85-3
• Molecular Formula: C12H8S2
• Molecular Weight: 216.33
• Purity: 99.97%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.11 mg/mL (5.13 mM); Clear solution
• Availability: In-stock

Source

Original product source