N-Isovalerylglycine-d 9

Overview

N-Isovalerylglycine-d 9 is the deuterium labeled N-Isovaleroylglycine ( HY-W015464 ). N-Isovaleroylglycine is a peptidylglycine α-amidating monooxygenase ( PAM ) inhibitor with a K i value of 2.0 mM against human hsPAM . N-Isovaleroylglycine undergoes oxidative cleavage by purified rat PAM to produce fatty acid amide and glyoxylic acid. N-Isovaleroylglycine exerts competitive inhibition by binding to hsPAM, blocking the amidation of dansyl-Tyr-Val-Gly. N-Isovaleroylglycine exhibits lowered urinary abundance in MRSA-infected mice, which qualifies it as a non-invasive biomarker. N-Isovaleroylglycine can be used in studies related to Staphylococcus aureus pneumonia and diabetic foot.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-W015464S
• CAS No.: 1330037-21-2
• Molecular Formula: C7H4D9NO3
• Molecular Weight: 168.24
• Purity: 99.0%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source