NAPQI

Overview

NAPQI is the toxic metabolite of Acetaminophen ( HY-66005 ). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Drug Metabolite | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-W017464
• CAS No.: 50700-49-7
• Molecular Formula: C8H7NO2
• Molecular Weight: 149.15
• Purity: 98.0%
• Storage: -80°C, protect from light, stored under nitrogen
• Availability: In-stock

Source

Original product source