Hexadecanedioic acid -d 28 is the deuterium labeled Hexadecanedioic acid ( HY-W018161 ). Hexadecanedioic acid (Thapsic acid) is an orally active metabolite produced by B. uniformis . Hexadecanedioic acid inhibits IRE1α-XBP1s -mediated flipogenesis and ferroptosis . Hexadecanedioic acid downregulates XBP1 and Hrd1 expression, activates the Nrf2/SLC7A11/GPX4 pathway. Hexadecanedioic acid can be used for the research of metabolic-associated fatty liver disease.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Keap1-Nrf2 | Products > Signaling Pathways > Glutathione Peroxidase | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > IRE1 | Products > Signaling Pathways > Ferroptosis
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