2,2-Dihydroxyacetic acid is an endogenous metabolite , which is the monohydrate of Glyoxylic Acid . 2,2-Dihydroxyacetic acid may participate in the microbial glyoxylate cycle, induce an increase in reactive oxygen species , promote cell differentiation, and modify proteins to form advanced glycation end products (AGEs) ( HY-NP165 ). 2,2-Dihydroxyacetic acid is associated with metabolic diseases such as primary hyperoxaluria.
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