6-Nitrophthalide

6-Nitrophthalide
  • CAS No.:610-93-5
Other grades of this product :
6-Nitrophthalide Basic information
Product Name:6-Nitrophthalide
Synonyms:RARECHEM AR PA 0038;6-NITRO-1,3-DIHYDROISOBENZOFURAN-1-ONE;6-NITRO-3H-ISOBENZOFURAN-1-ONE;6-NITROPHTALIDE;6-NITROPHTHALIDE;BUTTPARK 33\04-92;6-Nitrophthalide,97%;AKOS 237-80
CAS:610-93-5
MF:C8H5NO4
MW:179.13
EINECS:
Product Categories:Phthalides;Carbonyl Compounds;Lactones;Organic Building Blocks
Mol File:610-93-5.mol
6-Nitrophthalide Chemical Properties
Melting point 140-145 °C(lit.)
Boiling point 311.63°C (rough estimate)
density 1.4908 (rough estimate)
refractive index 1.5160 (estimate)
storage temp. Sealed in dry,Room Temperature
form Crystalline Powder
color Pale yellow
Water Solubility 0.4g/L(25 ºC)
CAS DataBase Reference610-93-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 20/21/22-36/37/38
Safety Statements 24/25-37-26
WGK Germany 3
HazardClass IRRITANT
HS Code 29322090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
6-Nitrophthalide Usage And Synthesis
Chemical Propertiespale yellow crystalline powder
Uses6-Nitrophthalide is a fluorescent heterocycle that can be used as a probe for specific inhibition. It is homologous to other fluorescent probes such as fluorescein, nitrobenzene, and nitrophenol. It has been shown to have inhibitory properties against triazole and dipole, which are catalytic asymmetric. 6-Nitrophthalide has also been shown to have the ability to inhibit the oxidation of aldehydes.
Preparation6-Nitrophthalide is synthesized from 2-nitrobenzaldehyde via a two-step process, and then reacted with methyl iodide.
Application6-Nitrophthalide has been used in the preparation of 3-bromo-6-nitrophthalide. It undergoes reductive methylation to form 6-dimethylaminophthalide.

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