IN04 is a inhibitor of leucine-rich repeat kinase 1 ( LRRK1 ). IN04 can completely block the binding of ATP to the human LRRK1 kinase domain, thereby inhibiting the kinase activity of LRRK1. IN04 can significantly impair the bone resorption ability of osteoclasts, with an IC 50 value of 5.72 μM. IN04 can be used for the study of osteoporosis.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Autophagy | Products > Research Areas > Endocrinology | Products > Signaling Pathways > LRRK2
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