p-SCN-Macropa is a bifunctional macrocyclic chelator featuring macrocyclic polyamine skeletons and thiocyanate (-SCN) reactive moieties. p-SCN-Macropa can conjugate with monoclonal antibodies including Nimotuzumab ( HY-P9968 ), Rituximab ( HY-P9913 ) and Trastuzumab ( HY-P9907 )-PEG6-DM1 for 225 Ac radiolabeling to construct radioimmunoconjugates. p-SCN-Macropa is applicable for the research of colorectal cancer , HER2-positive breast cancer , TROP-2-positive cancers, and PSMA-positive cancers.
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