Minoxidil

Melting point	272-274 °C (dec.) (lit.)
Boiling point	348.61°C (rough estimate)
density	1.1651 (rough estimate)
refractive index	1.7610 (estimate)
storage temp.	2-8°C
solubility	Slightly soluble in water, soluble in methanol and in propylene glycol.
form	neat
pka	4.61(at 25℃)
color	White
Water Solubility	Soluble in water (2.2 mg/ml), 100% ethanol (29 mg/ml), propylene glycol, acetone, DMSO (6.5 mg/ml), and methanol.
Merck	14,6203
Stability:	Stable for 2 years from date of purchase as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey	ZFMITUMMTDLWHR-UHFFFAOYSA-N
CAS DataBase Reference	38304-91-5(CAS DataBase Reference)
NIST Chemistry Reference	Minoxidil(38304-91-5)

Minoxidil is a peripheral vasodilator that directly relaxes vascular smooth musculature, thus, lowering systolic and diastolic pressure. Its action is linked to the activation of calcium channels. Open calcium channels cause hyperpolarization of smooth muscle cells, which in turn, reduces the flow of calcium ions into the cell, which is necessary for supporting vascular tonicity. However, when taking minoxidil, tachycardia, elevated renin secretion, and water and sodium ion retention all appear simultaneously with hypotension.