| Ambazone Basic information |
| Product Name: | Ambazone |
| Synonyms: | 1,4-Benzoquinone guanylhydrazone thiosemicarbazone;Faringosept;Inversal;((4-oxo-2,5-cyclohexadien-1-ylidene)amino)-guanidin thiosemicarbazone;((4-oxo-2,5-cyclohexadien-1-ylidene)amino)guanidine thiosemicarbazone;1-amidinohydrazono-4-thiosemicarbazono-2,5-cyclohexadiene;ambazon;anginon |
| CAS: | 539-21-9 |
| MF: | C8H11N7S |
| MW: | 237.28 |
| EINECS: | 208-713-0 |
| Product Categories: | Amines;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds |
| Mol File: | 539-21-9.mol |
| Ambazone Chemical Properties |
| Melting point | 195°C (rough estimate) |
| Boiling point | 160°C (rough estimate) |
| density | 1.2732 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Hygroscopic, Refrigerator, under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Red to Very Dark Brown |
| Stability: | Very Hygroscopic |
| EPA Substance Registry System | Hydrazinecarbothioamide, 2-[4-[(aminoiminomethyl)hydrazono]-2,5-cyclohexadien-1-ylidene]- (539-21-9) |
| Safety Information |
| MSDS Information |
| Ambazone Usage And Synthesis |
| Originator | Ambazone,Generic |
| Uses | Ambazone is a benzoquidine diimine derivative useful as animal growth substance. |
| Manufacturing Process | To a solution of 22.7 g of quinone monoguanylhydrazone nitrate in 250 ml water is added dropwise hot aqueous solution of 9.1 g thiosemicarbazide, then is added slowly a solution of 5 ml concentrated nitric acid in 10 ml of water. The mixture is stirred at 60°C for 1 hour. The product is dissolved in 1-1.2 L of water at 100°C. The solution is filtered and added to an aqueous ammonium solution. Blue residue of p-benzoquinone amidinohydrazone thiosemicarbazone is filtered and dried, melting point 188°C (decomp.). |
| Therapeutic Function | Antiseptic |
| Ambazone Preparation Products And Raw materials |
| Raw materials | Nitric acid-->thiosemicarbazide |
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