N'-Isonicotinoylisonicotinohydrazide

Overview

N'-Isonicotinoylisonicotinohydrazide (Compound 7, 1,2-Diisonicotinoylhydrazine) is a competitive inhibitor ( IC 50 =5-30 μM) of bacterial heme oxygenase ( HO ). N'-Isonicotinoylisonicotinohydrazide inhibits iron release and bacterial iron acquisition. N'-Isonicotinoylisonicotinohydrazide exhibits selective activity against HO enzymes from Pseudomonas aeruginosa and Neisseria meningitidis . N'-Isonicotinoylisonicotinohydrazide is promising for research of multidrug-resistant Gram-negative bacterial infections.

Application

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Product Information

• Catalog No.: HY-W354203
• CAS No.: 4329-75-3
• Molecular Formula: C12H10N4O2
• Molecular Weight: 242.23
• Purity: 99.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source