Other grades of this product :
| THENIUM CLOSYLATE Basic information |
| THENIUM CLOSYLATE Chemical Properties |
| Melting point | 159-160°C | | storage temp. | -20°C Freezer | | solubility | Acetonitrile (Slightly), Methanol, Water (Slightly) | | form | Solid | | color | White to Off-White | | CAS DataBase Reference | 4304-40-9 |
| THENIUM CLOSYLATE Usage And Synthesis |
| Chemical Properties | White Solid | | Originator | Thenium closylate,ZYF Pharm Chemical | | Uses | Active against parasitic nematodes, especially those of the stomach and intestines | | Uses | Active against parasitic nematodes, especially those of the stomach and intestines. | | Manufacturing Process | 2-Chlormethylthiophene (6.6 g) was added to a solution of 1-dimethylamino-
2-phenoxyethane (8.2 g) in acetone (45 ml). On standing for 30 min an oil
separeted. The resulting suspension was heated to reflux for a further 30 min
and cooled. On standing, the separated oil partially crystallized. The
supernatant liquors were decanted and the residue was recrystallized by
dissolution in warm isopropanol and careful precipitation with ethyl acetate or
ether to give colourless needles N,N-dimethyl-N-2-phenoxyethyl-N-2'-
thenylammonium chloride monohydrate, M.P. 85-86°C.A solution of free base of the last compound and p-chlorobenzenesulfonic acid
(molar ratio 1:1) were reacted together in boiling acetone. After 30 min the
solution was cooled and ethyl acetate added to precipitate a colourless solid of
N,N-dimethyl-N-(2-phenoxyethyl)-N-(2-thenyl)ammonium 4-
chlorbenzolsulfonate. | | Therapeutic Function | Anthelmintic |
| THENIUM CLOSYLATE Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye