Thalidomide-4-NH-PEG1-NH-Boc

Overview

Thalidomide -4-NH-PEG1-NH-Boc is a Boc-modified Thalidomide ( HY-14658 ) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide -4-NH-PEG1-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide -4-NH-PEG1-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > E3 Ligase Ligand-Linker Conjugates | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-W584520
• CAS No.: 2154342-17-1
• Molecular Formula: C22H28N4O7
• Molecular Weight: 460.48
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source