VH032 -NH-CO-CH2-NHBoc is a Boc-modified VH032 ( HY-120217 ) that acts as a ligand for VHL to recruit von Hippel-Lindau (VHL) proteins. VH032 -NH-CO-CH2-NHBoc will remove the Boc protection under acidic conditions, and connect with the target protein ligand through a linker to form a PROTAC molecule, which is a key intermediate for the synthesis of PROTAC based on VHL ligand.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Ligands for E3 Ligase
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