SDH-IN-43 (Compound i-19) is a succinate dehydrogenase ( SDH ) inhibitor. SDH-IN-43 shows potent inhibitory activity against caenorhabditis elegans wirh an IC 50 of 6.67 μM. SDH-IN-43 can significantly reduce caenorhabditis elegans reproductive ability and movement ability, and is also effective against drug-resistant strains of Levamisole ( HY-A0106 ), Benzimidazole ( HY-Y1825 ), and Ivermectin ( HY-15310 ). SDH-IN-43 can be used for the research of parasite infection .
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