| SALICYLIDENE SALICYLHYDRAZIDE Basic information |
| Product Name: | SALICYLIDENE SALICYLHYDRAZIDE |
| Synonyms: | 2-HYDROXYBENZYLIDENE SALICYLHYDRAZIDE;2-HYDROXYBENZYLIDENE 2-HYDROXYBENZHYDRAZIDE;2-hydroxy-benzoicaci[(2-hydroxyphenyl)methylene]hydrazide;(2-hydroxybenzylidene)salicylohydrazide;Salicylidenesalicylhydrazide,97%;2-Hydroxybenzylidene 2-hydroxybenzhydrazide, NSC 87864, SCS;SALICYLIDENE SALICYLHYDRAZIDE;SALICYLIDENE SALICYLHYDRAZONE |
| CAS: | 3232-36-8 |
| MF: | C14H12N2O3 |
| MW: | 256.26 |
| EINECS: | 221-773-2 |
| Product Categories: | GABA/Glycine receptor;Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes |
| Mol File: | 3232-36-8.mol |
| SALICYLIDENE SALICYLHYDRAZIDE Chemical Properties |
| Melting point | 280-284°C |
| storage temp. | Store at RT |
| solubility | DMSO: ~20 mg/mL |
| form | solid |
| color | off-white |
| BRN | 2944701 |
| CAS DataBase Reference | 3232-36-8(CAS DataBase Reference) |
| EPA Substance Registry System | Benzoic acid, 2-hydroxy-, [(2-hydroxyphenyl)methylene]hydrazide (3232-36-8) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36-37 |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29280000 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| ALFA | English |
| SALICYLIDENE SALICYLHYDRAZIDE Usage And Synthesis |
| Uses | SCS is a selective inhibitor of β1-containing GABAA receptors. |
| Biological Activity | Potent and selective partial inhibitor of β 1-containing GABA A receptors (IC 50 values are 4.5, 5.3 and 7.9 nM at α 2 β 1 γ 1 θ , α 2 β 1 γ 1 and α 2 β 1 γ 2s GABA A receptors respectively). May bind allosterically to a novel site on GABA A receptor. |
| SALICYLIDENE SALICYLHYDRAZIDE Preparation Products And Raw materials |
| Raw materials | SALICYLIC (ALPHA-METHYLBENZYLIDENE)HYDRAZIDE-->Salicylhydrazide-->Ethyl 2-hydroxybenzoate-->Methyl salicylate-->Salicylaldehyde-->Salicylic acid |
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