(R)-Brivanib alaninate-d 4 is the deuterium-labeled Brivanib (alaninate) ( HY-10336 ). Brivanib alaninate (BMS-582664) is an ATP-competitive inhibitor against VEGFR2 with an IC 50 of 25 nM; has moderate potency against VEGFR-1 and FGFR-1 , but more than 240-fold against PDGFRβ .
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