2-Deoxyuridine-1,2,3,4,5- 13 C 5

Overview

2-Deoxyuridine-1,2,3,4,5- 13 C 5 is the 13 C-labeled 2'-Deoxyuridine ( HY-D0186 ). 2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine ( HY-B1011 ) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU ( HY-118411 ). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD).

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Infection | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Endogenous Metabolite | Products > Signaling Pathways > Thymidylate Synthase

Product Information

• Catalog No.: HY-W778990
• CAS No.: 478510-94-0
• Molecular Formula: C413C5H12N2O5
• Molecular Weight: 233.17
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source