Matriptase-IN-2

Overview

Matriptase-IN-2 is a secondary amide inhibitor of matriptase derived from sulfonylated 3-amidinophenylalanine, with a K i value of 5 nM. Matriptase acts as a novel initiator of cartilage matrix degradation in osteoarthritis, and Matriptase-IN-2 inhibits matriptase-mediated cartilage degradation. Matriptase-IN-2 is applicable for the research of osteoarthritis.

Application

Products | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Arthritis | Products > Disease Areas > Osteoarthritis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Ser/Thr Protease

Product Information

• Catalog No.: HY-W783268A
• CAS No.: 1268874-09-4
• Molecular Formula: C33H35Cl2F6N5O7S
• Molecular Weight: 830.62
• Purity: 99.87%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (3.01 mM); Clear solution
• Availability: In-stock

Source

Original product source