D-myo-Inositol 1,4,5-trisphosphate sodium salt

Overview

D-myo-inositol 1,4,5-trisphosphate sodium salt is a widely distributed intracellular second messenger. D-myo-inositol 1,4,5-trisphosphate sodium salt acts as a potent agonist of the Ins (1,4,5) P 3 receptor with an EC 50 of 0.12 μM and inhibits bovine PLC-δ1 , with an IC 50 of 5.4 μM for binding and an IC 50 of 12.4 μM for hydrolysis. D-myo-inositol 1,4,5-trisphosphate sodium saltis metabolized into Ins (1,4) P 2 and Ins (1,3,4,5) P 4 . D-myo-inositol 1,4,5-trisphosphate sodium salt mediates various cellular processes, including growth, development, fertilization, secretion, contraction and neuromodulation. D-myo-inositol 1,4,5-trisphosphate sodium salt inhibits PIP 2 hydrolysis and Ca 2+ -ATPase activity. D-myo-inositol 1,4,5-trisphosphate sodium salt is used for cardiac preconditioning, exerts cardioprotective effects and mimics ischemic preconditioning. D-myo-inositol 1,4,5-trisphosphate sodium salt is applied in studies related to intracellular calcium and phosphoinositol signaling pathways.

Application

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Product Information

• Catalog No.: HY-W795960
• CAS No.: 108340-81-4
• Molecular Formula: C6H9Na6O15P3
• Molecular Weight: 551.99
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source