Azido-PEG8-Amido-Val-Cit-PAB

Overview

Azido-PEG8-Amido-Val-Cit-PAB is a cleavable ADC linker . The Val-Cit will specifically be cleaved by Cathepsin B . As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. Azido will react with DBCO, BCN or other alkyne groups through click chemistry. PEG spacer increases aqueous solubility. Reagent grade, for research purpose.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > ADC Linkers

Product Information

• Catalog No.: HY-W800814
• CAS No.: 2356229-77-9
• Molecular Formula: C40H69N9O15
• Molecular Weight: 916.03
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source