BWA-522 intermediate-1 is an intermediate in the synthesis of PROTAC BWA-522 ( HY-149433 ) and serves as a ligand molecule for cereblon E3 ubiquitin ligase . BWA-522 is an orally active small molecule protein-targeting chimera ( PROTAC ) that has significant degradation effects on AR-FL and AR-V7.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Ligands for E3 Ligase
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