ALT-2074 (BXT-51071) is an orally active catalytic analogue of glutathione peroxidase . ALT-2074 is an inhibitor of human CYP3A , with its IC 50 value ranging from 2.0 to 2.6 μM. ALT-2074 shows only a weak inhibitory effect on CYP3A in vivo, suggesting that it may not significantly affect the metabolism of CYP3A substrate drugs. ALT-2074 can be used to study inflammatory diseases characterized by reactive oxygen species , such as acute coronary syndrome.
Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Cytochrome P450 | Products > Signaling Pathways > Glutathione Peroxidase
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