2,3'-Dichloroacetophenone

CAS No.：21886-56-6

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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2,3'-Dichloroacetophenone Basic information

Product Name:	2,3'-Dichloroacetophenone
Synonyms:	3-CHLOROPHENACYL CHLORIDE;A,3-DICHLOROACETOPHENONE;α,3-DICHLOROACETOPHENONE;3-CHLORO-ALPHA-CHLOROACETOPHENONE;alpha ,3-Dichloroacetophenone;2,3''-DICHLOROACETOPHENONE 99+%;2,3'-Dichloroacetophenone;2-Chloro-1-(3-chlorophenyl)ethanone
CAS:	21886-56-6
MF:	C8H6Cl2O
MW:	189.04
EINECS:
Product Categories:
Mol File:	21886-56-6.mol

2,3'-Dichloroacetophenone Chemical Properties

Boiling point	283.7±20.0 °C(Predicted)
density	1.310±0.06 g/cm3(Predicted)
storage temp.	2-8°C
CAS DataBase Reference	21886-56-6(CAS DataBase Reference)
EPA Substance Registry System	Ethanone, 2-chloro-1-(3-chlorophenyl)- (21886-56-6)

Safety Information

Hazard Codes	C
HS Code	2914790090

MSDS Information

2,3'-Dichloroacetophenone Usage And Synthesis

Uses

2,3''-Dichloroacetophenone is used as a reagent in the synthesis of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β). Also used as a reagent in the synthesis of benzimidazolyl pyridinones as insulin-like growth factor I (IGF-1R) kinase inhibitors.

2,3'-Dichloroacetophenone Preparation Products And Raw materials

Raw materials

Benzene, 1-chloro-3-(2-chloroethynyl)--->Ethanone, 2,2-dichloro-1-(3-chlorophenyl)--->Ethanone, 2-(acetyloxy)-1-(3-chlorophenyl)--->Ethanone, 1-(3-chlorophenyl)-2-hydroxy--->3-CHLOROPHENACYL BROMIDE-->3-Chlorophenylacetylene-->3-Chlorostyrene-->Methanol-->3-BROMOCHLOROBENZENE-->3-Chlorobenzoic acid-->3'-Chloroacetophenone

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