PVA (Polyvinyl alcohol; Poly(Ethenol)) (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization) is a semicrystalline synthetic polymer with excellent biocompatibility and biodegradability, which is non-toxic and non-mutagenic upon oral administration in the human body. PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization) can serve as an excipient, inhibitor or coating agent to prepare solid dispersions by absorbing water and inhibiting drug crystal nucleation and growth, and can encapsulate insulin-like growth factor-1. PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization) can form physically crosslinked cryogels and degradable films, and is widely used in the construction of vascular grafts, the synthesis of articular cartilage, and studies on dry or minimally invasive ex vivo wounds. PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization) also promotes hydrogen peroxide generation and enhances the redox cycle of iron species, thus acting as a sacrificial agent to effectively degrade pollutants.
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