Hydroxyacetone

Overview

Hydroxyacetone is a toxic compound. Hydroxyacetone can be isolated from e-cigarette aerosols. Hydroxyacetone reduces the activity of cellular Mitochondrial reductase (with an IC 50 of 5.53 mg/mL for mitochondrial reductase in BEAS-2B cells) and increases ROS levels. Hydroxyacetone induces mitochondrial stress and oxidative damage. Hydroxyacetone induces destabilization of F-actin . At high concentrations, Hydroxyacetone promotes cell rounding and Apoptotic body formation. Hydroxyacetone exerts toxic effects on cells including airway epithelial cells and possesses respiratory toxicity potential.\n

Application

Products | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Upper Respiratory Inflammation | Products > Disease Areas > Lower Respiratory Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Mitochondrial Metabolism | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Arp2/3 Complex

Product Information

• Catalog No.: HY-Y1366
• CAS No.: 116-09-6
• Molecular Formula: C3H6O2
• Molecular Weight: 74.08
• Purity: 98.93%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (33.75 mM); Clear solution
• Availability: In-stock

Source

Original product source