Isoimperatorin is a COX-2 inhibitor, and also inhibits cytochrome P450 (CYP) isoform 1A activity. In bone marrow-derived mast cells, isoimperatorin exhibits an inhibitory effect on degranulation. Isoimperatorin suppresses proliferation in melanoma cells. Source summary: Isoimperatorin is a research-use natural product (furanocoumarin) for biochemical studies, available as a small-molecule reagent.
Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Inflammation / Immunology | Cox-2
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