Ruxolitinib

Overview

Ruxolitinib is a potent and selective JAK1/2 inhibitor with IC50 values of 3.3 nM and 2.8 nM respectively in cell-free assays, and has > 130-fold selectivity for JAK1/2 versus JAK3.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Inflammation / Immunology | JAK

Product Information

• Catalog No.: B0084-156872
• CAS No.: 941678-49-5
• Molecular Formula: C17H18N6
• Molecular Weight: 306.37
• Purity: >98%
• Solubility: Soluble in aqueous buffers across a pH of 1-8

Source

Original product source