Crisaborole is a novel PDE-4 inhibitor used as a nonsteroidal topical medication for the treatment of mild-to-moderate atopic dermatitis (eczema). Crisaborole selectively inhibits PDE-4B which mainly leads to inflammation. Tumor necrosis factor alpha (TNFα), interleukin-12 (IL-12), IL-23 and other cytokines are also suppressed while crisaborole functioning.
Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Inflammation / Immunology | PDE4
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