Afatinib Dimaleate irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively.
Products > Drug Discovery > Impurities > Anti-Neoplastic > Afatinib and Impurities | Products > Drug Discovery > Inhibitor
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