JNJ 0966 is a selective inhibitor of MMP-9 (IC50 = 440 nM) with no effect on MMP-1, MMP-2, MMP-3, MMP-9, or MMP-14 catalytic activity. JNJ 0966 was indicated to alleviate the pain of experimental autoimmune encephalomyelitis in a mouse model.
Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cardiovascular and blood system | MMP
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