IACS-010759 is an orally bioavailable inhibitor of mitochondrial oxidative phosphorylation (OXPHOS), targeting complex I of the electron transport chain (NADH ubiquinone oxidoreductase). Study showed that IACS-010759 induced AMPK activation leading to mTOR suppression which resulted in cell growth inhibition in AML cells.
Products > Drug Discovery > Inhibitor > Other Inhibitors | Products > Drug Discovery > Inhibitor
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