O-Desmethyl apixaban sulfate is the major circulating metabolite of Apixaban ( HY-50667 ) in humans. O-Desmethyl apixaban sulfate exhibits no inhibitory activity against human activated factor X (FXa), with a K i > 20 μM.
Products | Products > Disease Areas > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Drug Metabolite | Products > Signaling Pathways > Factor Xa
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