JH-X-119-01 (Standard)

JH-X-119-01 (Standard)
  • CAS No.:2227368-54-7
  • Formula:C25H20N6O3
  • M.W.:452.46

Overview

JH-X-119-01 (Standard) is the analytical standard of JH-X-119-01 ( HY-103017A ). This product is intended for research and analytical applications. JH-X-119-01 is a potent and selective interleukin-1 receptor-associated kinases 1 ( IRAK1 ) inhibitor. JH-X-119-01 ameliorates LPS-induced sepsis in mice. JH-X-119-01 inhibits IRAK1 biochemically with an apparent IC 50 of 9 nM while exhibiting no inhibition of IRAK4 at concentrations up to 10 μM.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > IRAK

Product Information

  • Catalog No.: HY-103017AR
  • CAS No.: 2227368-54-7
  • Molecular Formula: C25H20N6O3
  • Molecular Weight: 452.46
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


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