Gusacitinib (Standard)

Overview

Gusacitinib (Standard) is the analytical standard of Gusacitinib ( HY-103018 ). This product is intended for research and analytical applications. Gusacitinib (ASN-002) is an orally active dual SYK/JAK kinase inhibitor with IC 50 values of 5, 46, 4, 11 and 8 nM for SYK , JAK1 , JAK2 , JAK3 and TYK2 , respectively. Gusacitinib rapidly and significantly suppressed key inflammatory pathways implicated in atopic dermatitis pathogenesis. Gusacitinib can be used in the research of chronic hand eczema and cancers such as basal cell carcinoma.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > JAK | Products > Signaling Pathways > Syk

Product Information

• Catalog No.: HY-103018R
• CAS No.: 1425381-60-7
• Molecular Formula: C24H28N8O2
• Molecular Weight: 460.53
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source