I-XW-053 (Standard)

I-XW-053 (Standard)
  • CAS No.:5496-35-5
  • Formula:C22H16N2O2
  • M.W.:340.38

Overview

I-XW-053 (Standard) is the analytical standard of I-XW-053 ( HY-103078 ). This product is intended for research and analytical applications. I-XW-053 is a specific anti- HIV-1 capsid inhibitor ( IC 50 =164.2 μM). By binding to the CA NTD-NTD hexamerization interface and the R173 region of CTD ( K d =66.3 μM), I-XW-053 disrupts capsid function and reduces polymerization levels. I-XW-053 effectively blocks HIV-1 uncoating, inhibits reverse transcription and early replication, and exhibits broad-spectrum activity against primary HIV-1 isolates in peripheral blood mononuclear cells. I-XW-053 can be widely used in studies related to HIV-1 infection.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > HIV | Products > Signaling Pathways > Reverse Transcriptase

Product Information

  • Catalog No.: HY-103078R
  • CAS No.: 5496-35-5
  • Molecular Formula: C22H16N2O2
  • Molecular Weight: 340.38
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


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