CMF019 (Standard)

Overview

CMF019 (Standard) is the analytical standard of CMF019 ( HY-103080 ). This product is intended for research and analytical applications. CMF019 is an orally active, potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pK i values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents. Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin. CMF019 is promising for research of chronic diseases, such as, pulmonary arterial hypertension.

Application

Products | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Others | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Apelin Receptor (APJ) | Products > Signaling Pathways > Reference Standards

Product Information

• Catalog No.: HY-103080R
• CAS No.: 1586787-08-7
• Molecular Formula: C25H33N3O3S
• Molecular Weight: 455.61
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source