NAS-181 dimesylate (Standard)

Overview

NAS-181 dimesylate (Standard) is the analytical standard of NAS-181 dimesylate ( HY-103156 ). This product is intended for research and analytical applications. NAS181 is a potent and selective antagonist of rat 5-HT1B receptor, with a K i of 47 nM. NAS181 shows 13-fold selectivity for r5-HT1B over bovine 5-HT1B receptor (Ki=630 nM). NAS181 increases the 5-HT turnover and the synaptic concentration of 5-HT by inhibiting terminal r5-HT1B autoreceptors.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > 5-HT Receptor

Product Information

• Catalog No.: HY-103156R
• CAS No.: 1217474-40-2
• Molecular Formula: C21H34N2O10S2
• Molecular Weight: 538.63
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source