Other grades of this product :
| 1400W Chemical Properties |
| Melting point | 208-220 °C | | Boiling point | 301.7±44.0 °C(Predicted) | | density | 1.09±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | DMSO, Methanol, Water | | pka | 11.33±0.50(Predicted) | | form | solid | | color | White to Off-White |
| 1400W Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | A selective inducible nitric oxide synthase (iNOS) inhibitor. A long-acting human iNOS inhibitor possessing an IC50 value of 2.0uM | | Uses | 1400W selectively inhibits inducible nitric oxide synthase. W 1400 has been implicated to prevent Doxorubicin and Trastuzumab induced cardiotoxicity. | | Biological Activity | Slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (K d = 7 nM). Selective over nNOS and eNOS (K i values are 2 and 50 μ M respectively). Cell-permeable and active in vivo . |
| 1400W Preparation Products And Raw materials |
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