CHM-1 (Standard) is the analytical standard of CHM-1 ( HY-103257 ). This product is intended for research and analytical applications. CHM-1 , a microtubule-destabilizing agent, inhibits tubulin polymerization. CHM-1 is a potent and selective antimitotic antitumor activity against human hepatocellular carcinoma. CHM-1 induces growth inhibition and apoptosis via G2-M phase arrest in human hepatocellular carcinoma cells by activation of Cdc2 kinase activity.
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