DCPIB (Standard)

Overview

DCPIB (Standard) is the analytical standard of DCPIB ( HY-103371 ). This product is intended for research and analytical applications. DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC). DCPIB voltage-dependently activates potassium channels TREK1 and TRAAK, and inhibits TRESK, TASK1 and TASK3 (IC 50 s: 0.14, 0.95, 50.72 μM, respectively). DCPIB is also a selective blocker of swelling-induced chloride current (ICl,swell), with an IC 50 of 4.1 μM. DCPIB is a useful tool for investigating structure-function studies of K2P channels.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Chloride Channel | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-103371R
• CAS No.: 82749-70-0
• Molecular Formula: C22H28Cl2O4
• Molecular Weight: 427.36
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source