SKF-83566 (Standard)

Overview

SKF-83566 (Standard) is the analytical standard of SKF-83566 ( HY-103430A ). This product is intended for research and analytical applications. SKF-83566 is a potent, blood-brain permeable and orally active D1-like dopamine receptor (D1DR) antagonist and a weaker competitive antagonist at the vascular 5-HT2 receptor (Ki=11 nM). SKF-83566 is a competitive DAT ( dopamine transporter ) inhibitor with an IC 50 of 5.7 μM. SKF-83566 also shows selective inhibition for adenylyl cyclase 2 (AC2) over AC1 and AC5 in the isolated rabbit thoracic aorta. SKF-83566 can be used for research of parkinson’s disease and nicotine craving alleviation.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Dopamine Receptor | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > Adenylate Cyclase

Product Information

• Catalog No.: HY-103430AR
• CAS No.: 99295-33-7
• Molecular Formula: C17H18BrNO
• Molecular Weight: 332.23
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source