Bicuculline methiodide (Standard)

Overview

Bicuculline methiodide (Standard) is the analytical standard of Bicuculline methiodide ( HY-103474 ). This product is intended for research and analytical applications. Bicuculline methiodide ((-)-Bicuculline methiodide) is a potent GABAA blocker. Bicuculline methiodide alters membrane properties and firing pattern. Bicuculline methiodide reduces the Apamin-sensitive afterhyperpolarization, while Apamin is a toxin isolated from bee venom to block small conductance Ca2+ -activated K+ channels. Bicuculline methiodide facilitates burst firing via blocking apamin-sensitive Ca2+ -activated K+ current.

Application

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Product Information

• Catalog No.: HY-103474R
• CAS No.: 40709-69-1
• Molecular Formula: C21H20INO6
• Molecular Weight: 509.29
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source