LY456236 (Standard)

Overview

LY456236 (Standard) is the analytical standard of LY456236 ( HY-103566 ). This product is intended for research and analytical applications. LY456236 is a selective, non-competitive and orally active antagonist of glutamate receptor 1 (mGlu1), which can inhibit phosphatidylinositol hydrolysis with an IC 50 of 0.145 μM. LY456236 can also inhibit EGFR , with an IC 50 of 0.918 μM. LY456236 has anticonvulsant effects and blocks cell proliferation by inhibiting the MAPK pathway, reversing the anti-apoptotic effect of DHPG ( HY-12598A ). LY456236 can be used in epilepsy research.

Application

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Product Information

• Catalog No.: HY-103566R
• CAS No.: 338736-46-2
• Molecular Formula: C16H16ClN3O2
• Molecular Weight: 317.78
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source