Trimetrexate (Standard)

Overview

Trimetrexate (Standard) is the analytical standard of Trimetrexate ( HY-10373 ). This product is intended for research and analytical applications. Trimetrexate (CI-898) is an antibiotic , also a potent and orally active dihydrofolate reductase (DHFR) inhibitor , reducing the production of DNA and RNA precursors and leading to cell death, with IC 50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer .

Application

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Product Information

• Catalog No.: HY-10373R
• CAS No.: 52128-35-5
• Molecular Formula: C19H23N5O3
• Molecular Weight: 369.42
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source