Lydimycin (α-DHB; α-Dehydrobiotin) is an antibiotic produced by Streptomyces lydicus , with antibacterial , antifungal and antiviral activities. Lydimycin inhibits the binding of SARS-CoV-2 S-614G spike protein to human ACE2 . The antibacterial activity of Lydimycin can be reversed by Biotin ( HY-B0511 ) in the culture medium. Lydimycin is applicable to infection-related research.
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