Zamicastat (Standard)

Overview

Zamicastat (Standard) is the analytical standard of Zamicastat ( HY-106004 ). This product is intended for research and analytical applications. Zamicastat (BIA 5-1058) is a dopamine β-hydroxylase (DBH) inhibitor and can cross the blood-brain barrier (BBB) to cause central as well as peripheral effects. Zamicastat is also a concentration-dependent dual P-gp and BCRP inhibitor with IC 50 values of 73.8 μM and 17.0 μM, respectively. Zamicastat reduces high blood pressure.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Dopamine β-hydroxylase | Products > Signaling Pathways > P-glycoprotein | Products > Signaling Pathways > BCRP

Product Information

• Catalog No.: HY-106004R
• CAS No.: 1080028-80-3
• Molecular Formula: C21H21F2N3OS
• Molecular Weight: 401.47
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source