Ponalrestat (Standard)

Overview

Ponalrestat (Standard) (ICI 128436 (Standard)) is the analytical standard of Ponalrestat ( HY-106697 ). This product is intended for research and analytical applications. Ponalrestat (ICI 128436) is an orally active, selective and noncompetitive aldose reductase (AKR1B1; ALR) inhibitor. Ponalrestat selectively inhibits ALR2 (K i =7.7 nM) over ALR1 (K i =60 μM). Ponalrestat inhibits the conversion of glucose to sorbitol.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Aldose Reductase

Product Information

• Catalog No.: HY-106697R
• CAS No.: 72702-95-5
• Molecular Formula: C17H12BrFN2O3
• Molecular Weight: 391.19
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source