Pelrinone

Overview

Pelrinone is an orally active cardiotonic agent and PDE III inhibitor with an IC 50 of 36 μM. Pelrinone elevates intracellular cAMP levels. The action of Pelrinone is independent of β-adrenergic receptors, and it does not inhibit Na + /K + -ATPase. Pelrinone exerts positive inotropic and vasodilatory effects. Pelrinone inhibits platelet aggregation, reduces thrombus formation, and exerts weak anticoagulant activity without altering hematocrit or circulating platelet counts. Pelrinone can be used in research related to congestive heart failure and coronary thrombosis.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Blood Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Heart Disease | Products > Disease Areas > Platelet Disease | Products > Disease Areas > Heart Failure | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Phosphodiesterase (PDE)

Product Information

• Catalog No.: HY-106830
• CAS No.: 94386-65-9
• Molecular Formula: C12H11N5O
• Molecular Weight: 241.25
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source