PF-376304

Overview

PF-376304 is an orally active non-specific class I phosphoinositide 3-kinase ( PI3K ) inhibitor with an IC 50 of 0.197 μM against PI3Kγ . PF-376304 induces dose-dependent glucose and lipid metabolic disorders in rats, causes rapid death at high doses, and leads to metabolic abnormalities that are self-reversible at low doses. PF-376304 is applicable to the research of metabolic and inflammatory diseases.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > PI3K

Product Information

• Catalog No.: HY-107387
• CAS No.: 851757-93-2
• Molecular Formula: C17H24N8O3
• Molecular Weight: 388.43
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source